LAMA_000221800

Enolase, N-terminal domain/Enolase, C-terminal TIM barrel domain/Enolase C-terminal domain-like, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100260 OG7: OG7_0002539 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000190100
Aminotransferase class I and II, putative
— Both
LAMA_000278000
Aconitase family (aconitate hydratase)/Aconit
— Both
LAMA_000102800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000475100
Transketolase, thiamine diphosphate binding d
— Both
LAMA_000811200 ⚠
CS domain containing protein, putative
— Both
LAMA_000374200
Metalloenzyme superfamily/BPG-independent PGA
— Both
LAMA_000326400
haloacid dehalogenase-like hydrolase/Eukaryot
— Both
LAMA_000731400 ⚠
CS domain containing protein, putative
— Both
LAMA_000289600
Glutamate-cysteine ligase, putative
— Both
LAMA_000065400
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000072200
Rhodanese-like domain/Domain of unknown funct
— Both
LAMA_000420700
SEP domain containing protein, putative
— Both
LAMA_000383500
CTP synthase N-terminus/Glutamine amidotransf
— Both
LAMA_000228100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000192700 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000498900 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000505400 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000246900
Aspartate/ornithine carbamoyltransferase, car
— Both
LAMA_000107000
ERG2 and Sigma1 receptor like protein, putati
— Both
LAMA_000106000 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— Both
LAMA_000800100
Shikimate / quinate 5-dehydrogenase/3-hydroxy
— Both
LAMA_000475600
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000510000
Aspartate-ammonia ligase, putative
— Both
LAMA_000443600 ⚠
Thiolase, N-terminal domain/Beta-ketoacyl syn
— Both
LAMA_000797400
FGGY family of carbohydrate kinases, N-termin
— Both
LAMA_000523600
Aminotransferase class-V/Cys/Met metabolism P
— Both
LAMA_000280100
Citrate synthase, C-terminal domain containin
— Both
LAMA_000456800 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000461500 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000461400 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000070400
Phosphorylase superfamily, putative
— Both
LAMA_000109000 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000013900
D-isomer specific 2-hydroxyacid dehydrogenase
— +2 more Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.