LAMA_000192700

Peptidase M1 N-terminal domain/Peptidase family M1 domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_156775 OG7: OG7_0001210 29 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 29 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000221800 ⚠
Enolase, N-terminal domain/Enolase, C-termina
— OG7
LAMA_000065400 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000768300 ⚠
Transketolase, pyrimidine binding domain/Tran
— OG7
LAMA_000147800 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000194500 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— OG7
LAMA_000213400 ⚠
Threonine synthase N terminus, putative
— OG7
LAMA_000078600 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000376700 ⚠
Bromodomain, putative
— OG7
LAMA_000521400 ⚠
Methyltransferase domain containing protein,
— OG7
LAMA_000544900 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
LAMA_000375200 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000336100 ⚠
Bromodomain, putative
— OG7
LAMA_000020000 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— OG7
LAMA_000340400 ⚠
Bromodomain, putative
— OG7
LAMA_000118100 ⚠
DinB superfamily/Sulfatase-modifying factor e
— OG7
LAMA_000330400 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000190100 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG7
LAMA_000016400 ⚠
Dihydrofolate reductase/Thymidylate synthase,
— OG7
LAMA_000070400 ⚠
Phosphorylase superfamily, putative
— OG7
LAMA_000246900 ⚠
Aspartate/ornithine carbamoyltransferase, car
— OG7
LAMA_000443600 ⚠
Thiolase, N-terminal domain/Beta-ketoacyl syn
— OG7
LAMA_000510000 ⚠
Aspartate-ammonia ligase, putative
— OG7
LAMA_000228100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000475600 ⚠
Hydroxymethylglutaryl-coenzyme A synthase N t
— OG7
LAMA_000800100 ⚠
Shikimate / quinate 5-dehydrogenase/3-hydroxy
— OG7
LAMA_000383500 ⚠
CTP synthase N-terminus/Glutamine amidotransf
— OG7
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.