LAMA_000330400

Aminotransferase class I and II, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101502 OG7: OG7_0001321 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000543600 ⚠
Phosphotransferase enzyme family/Choline/etha
— OG7
LAMA_000710000 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000719600
Polysaccharide biosynthesis protein/NAD depen
— Both
LAMA_000088300
Insulinase (Peptidase family M16)/Peptidase M
— Both
LAMA_000194500 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— Both
LAMA_000505400 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— Both
LAMA_000307700
SET domain containing protein, putative
— Both
LAMA_000703200 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000340400 ⚠
Bromodomain, putative
— OG7
LAMA_000106000 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000498700 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000104400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000504100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000801900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000792600 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000781600 ⚠
Phosphotransferase enzyme family/Choline/etha
— Both
LAMA_000192700 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000376700 ⚠
Bromodomain, putative
— OG7
LAMA_000537300
WD domain, G-beta repeat, putative
— OG7
LAMA_000655200 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000375500 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000201300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000398600 ⚠
Insulinase (Peptidase family M16), putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000752000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000236800 ⚠
Cyclic nucleotide-binding domain/PAS fold/Pro
— OG7
LAMA_000780900 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— OG7
LAMA_000351800 ⚠
Peptidase family M3, putative
— OG7
LAMA_000571100
Thiamine pyrophosphate enzyme, N-terminal TPP
— Both
LAMA_000523600
Aminotransferase class-V/Cys/Met metabolism P
— Both
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— Both
LAMA_000031900 ⚠
Insulinase (Peptidase family M16)/Peptidase M
— Both
LAMA_000768300
Transketolase, pyrimidine binding domain/Tran
— Both
LAMA_000592200
Cytochrome b5-like Heme/Steroid binding domai
— OG6
LAMA_000040500 ⚠
Peptidase family M3, putative
— Both
LAMA_000517300 ⚠
Peptidase family M3, putative
— Both
LAMA_000336100 ⚠
Bromodomain, putative
— Both
LAMA_000016400
Dihydrofolate reductase/Thymidylate synthase,
— Both
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LAMA_000746500
Cofilin/tropomyosin-type actin-binding protei
— Both
LAMA_000072200
Rhodanese-like domain/Domain of unknown funct
— Both
LAMA_000320300
The ARF-like 2 binding protein BART, putative
— Both
LAMA_000342600 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000722400 ⚠
Peptidase M16 inactive domain containing prot
— Both
LAMA_000199100
U-box domain containing protein, putative
— Both
LAMA_000670800
NAD synthase, putative
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.