LAMA_000351800

Peptidase family M3, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102110 OG7: OG7_0002961 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000015600 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— Both
LAMA_000433400 ⚠
Calcineurin-like phosphoesterase, putative
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730600 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730500 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000263600 ⚠
Calcineurin-like phosphoesterase, putative
— OG7
LAMA_000055800 ⚠
Spermidine synthase tetramerisation domain/Sp
— OG7
LAMA_000084900 ⚠
DeoC/LacD family aldolase, putative
— OG7
LAMA_000125700 ⚠
FHA domain containing protein, putative
— OG7
LAMA_000296700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000413600 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000373300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000033700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000141900 ⚠
AAA domain (dynein-related subfamily)/AAA dom
— OG7
LAMA_000195200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000475100 ⚠
Transketolase, thiamine diphosphate binding d
— OG7
LAMA_000234800 ⚠
Inositol monophosphatase family, putative
— OG7
LAMA_000236800 ⚠
Cyclic nucleotide-binding domain/PAS fold/Pro
— OG7
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG7
LAMA_000537300 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000694500 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000719600 ⚠
Polysaccharide biosynthesis protein/NAD depen
— OG7
LAMA_000246900 ⚠
Aspartate/ornithine carbamoyltransferase, car
— OG7
LAMA_000543600 ⚠
Phosphotransferase enzyme family/Choline/etha
— OG7
LAMA_000375200 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000427800 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000147800 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000078600 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000330400 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000718000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000112700 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG7
LAMA_000087600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000199400 ⚠
Metallopeptidase family M24, putative
— OG7
LAMA_000230700 ⚠
Ecotin, putative
— OG7
LAMA_000291300 ⚠
Metallopeptidase family M24, putative
— OG7
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000089400 ⚠
Phosphotyrosyl phosphate activator (PTPA) pro
— OG7
LAMA_000422600 ⚠
FHA domain/Inner membrane component of T3SS,
— OG7
LAMA_000228800 ⚠
Ecotin, putative
— OG7
LAMA_000402000 ⚠
Phosphoglucomutase/phosphomannomutase, alpha/
— Both
LAMA_000771600 ⚠
Enoyl-CoA hydratase/isomerase, putative
— Both
LAMA_000495100 ⚠
hypothetical protein, conserved
— Both
LAMA_000702600 ⚠
WD domain, G-beta repeat, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.