LAMA_000413600

DEAD/DEAH box helicase/Type III restriction enzyme, res subunit/Helicase conserved C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101150 OG7: OG7_0000130 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000199400 ⚠
Metallopeptidase family M24, putative
— OG7
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000713100 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000691700 ⚠
Enoyl-CoA hydratase/isomerase, putative
— OG7
LAMA_000757600 ⚠
Amidinotransferase, putative
— OG7
LAMA_000633000 ⚠
Biotin/lipoate A/B protein ligase family, put
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000014600 ⚠
NAD(P)-binding Rossmann-like domain/Flavin co
— OG7
LAMA_000396800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000492200 ⚠
ADP-ribosylation factor family/Ras of Complex
— OG7
LAMA_000434700 ⚠
AhpC/TSA family/Redoxin/C-terminal domain of
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000351800 ⚠
Peptidase family M3, putative
— OG7
LAMA_000621100 ⚠
Mago nashi protein, putative
— OG7
LAMA_000296700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000125700 ⚠
FHA domain containing protein, putative
— OG7
LAMA_000730500 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000433400 ⚠
Calcineurin-like phosphoesterase, putative
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000228800 ⚠
Ecotin, putative
— OG7
LAMA_000422600 ⚠
FHA domain/Inner membrane component of T3SS,
— Both
LAMA_000084900 ⚠
DeoC/LacD family aldolase, putative
— Both
LAMA_000230700 ⚠
Ecotin, putative
— Both
LAMA_000475600 ⚠
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000040500 ⚠
Peptidase family M3, putative
— Both
LAMA_000517300 ⚠
Peptidase family M3, putative
— Both
LAMA_000055800 ⚠
Spermidine synthase tetramerisation domain/Sp
— Both
LAMA_000373300 ⚠
hypothetical protein, conserved
— Both
LAMA_000501700
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000015600 ⚠
UTP--glucose-1-phosphate uridylyltransferase,
— Both
LAMA_000730600 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000263600 ⚠
Calcineurin-like phosphoesterase, putative
— Both
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000089400 ⚠
Phosphotyrosyl phosphate activator (PTPA) pro
— Both
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000291300 ⚠
Metallopeptidase family M24, putative
— Both
LAMA_000298300 ⚠
CAP-Gly domain containing protein, putative
— OG7
LAMA_000298400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000277500 ⚠
Ubiquitin-like domain/CAP-Gly domain containi
— OG7
LAMA_000593600 ⚠
DJ-1/PfpI family, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.