LAMA_000199400

Metallopeptidase family M24, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146697 OG7: OG7_0006554 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LAMA_000033700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000422600 ⚠
FHA domain/Inner membrane component of T3SS,
— OG7
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000014900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000199500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000040500 ⚠
Peptidase family M3, putative
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000351800 ⚠
Peptidase family M3, putative
— OG7
LAMA_000433400 ⚠
Calcineurin-like phosphoesterase, putative
— OG7
LAMA_000263600 ⚠
Calcineurin-like phosphoesterase, putative
— OG7
LAMA_000228800 ⚠
Ecotin, putative
— OG7
LAMA_000230700 ⚠
Ecotin, putative
— OG7
LAMA_000020200 ⚠
PCI domain/Proteasome regulatory subunit C-te
— OG7
LAMA_000126000 ⚠
hypothetical protein, conserved
— Both
LAMA_000022700 ⚠
Ribosomal protein L19e, putative
— Both
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— Both
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000434800
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000686700 ⚠
Ribosomal protein L3, putative
— Both
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— Both
LAMA_000654400 ⚠
hypothetical protein, conserved
— Both
LAMA_000364800 ⚠
hypothetical protein, conserved
— Both
LAMA_000415600 ⚠
5'-3' exonuclease, N-terminal resolvase-like
— Both
LAMA_000064000 ⚠
Ferrous iron transport protein B/50S ribosome
— Both
LAMA_000103800 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000359700 ⚠
hypothetical protein, conserved
— Both
LAMA_000798700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LAMA_000094400 ⚠
hypothetical protein, conserved
— Both
LAMA_000180200 ⚠
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000008900 ⚠
DNA polymerase family A, putative
— OG6
LAMA_000024100 ⚠
Ribosomal protein L13e, putative
— Both
LAMA_000199900 ⚠
Ubiquitin family, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.