LAMA_000427800

Kelch motif containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_138459 OG7: OG7_0001012 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000115100 ⚠
Clp amino terminal domain, pathogenicity isla
— Both
LAMA_000040200 ⚠
ATPase family associated with various cellula
— Both
LAMA_000777300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000452400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000620400 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000753600 ⚠
Protein kinase domain containing protein, put
— OG7
LAMA_000461200 ⚠
HAD domain in Swiss Army Knife RNA repair pro
— OG7
LAMA_000306800 ⚠
mRNA capping enzyme, putative
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000566800 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000196000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000122000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000512800 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000087600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000090300 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG7
LAMA_000112700 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG7
LAMA_000562800 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000358700 ⚠
Glycosyl hydrolase family 65, N-terminal doma
— OG7
LAMA_000242000 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000213000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000746000 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LAMA_000693600 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000319800 ⚠
Cell division protein 48 (CDC48), N-terminal
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000186800 ⚠
SAC3/GANP family, putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000234800 ⚠
Inositol monophosphatase family, putative
— OG7
LAMA_000738700 ⚠
Myosin head (motor domain), putative
— OG7
LAMA_000506300 ⚠
Nucleotidyltransferase domain/RNA editing 3'
— OG7
LAMA_000495500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000539600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000685500 ⚠
Leucine-rich repeat/Leucine Rich repeats (2 c
— OG7
LAMA_000517300 ⚠
Peptidase family M3, putative
— OG7
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000281400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000351800 ⚠
Peptidase family M3, putative
— OG7
LAMA_000052600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000179100 ⚠
AAA domain (Cdc48 subfamily)/ATPase family as
— OG7
LAMA_000303100 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000377600 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.