LAMA_000443600

Thiolase, N-terminal domain/Beta-ketoacyl synthase, N-terminal domain/Thiolase, C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101329 OG7: OG7_0003757 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000291200
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000079800 ⚠
U-box domain containing protein, putative
— OG7
LAMA_000505400 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000192700 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— OG7
LAMA_000383500 ⚠
CTP synthase N-terminus/Glutamine amidotransf
— Both
LAMA_000475600 ⚠
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000800100 ⚠
Shikimate / quinate 5-dehydrogenase/3-hydroxy
— Both
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— Both
LAMA_000342600 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000070400 ⚠
Phosphorylase superfamily, putative
— Both
LAMA_000564200 ⚠
ATP cone domain/Ribonucleotide reductase, all
— Both
LAMA_000106000 ⚠
Peptidase M1 N-terminal domain/Peptidase fami
— Both
LAMA_000159700 ⚠
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000189200 ⚠
Phosphoglucose isomerase, putative
— Both
LAMA_000120600 ⚠
U-box domain containing protein, putative
— Both
LAMA_000747400 ⚠
Amino-transferase class IV, putative
— Both
LAMA_000503900 ⚠
Phosphoribosyl transferase domain containing
— Both
LAMA_000278000 ⚠
Aconitase family (aconitate hydratase)/Aconit
— Both
LAMA_000335700 ⚠
ATP-grasp domain/CoA-ligase, putative
— Both
LAMA_000510000 ⚠
Aspartate-ammonia ligase, putative
— Both
LAMA_000246900 ⚠
Aspartate/ornithine carbamoyltransferase, car
— Both
LAMA_000221800 ⚠
Enolase, N-terminal domain/Enolase, C-termina
— Both
LAMA_000499500 ⚠
CoA binding domain/Succinyl-CoA ligase like f
— Both
LAMA_000598700 ⚠
Phosphomethylpyrimidine kinase/pfkB family ca
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.