LAMA_000499500

CoA binding domain/Succinyl-CoA ligase like flavodoxin domain/CoA-ligase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100834 OG7: OG7_0005210 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000335700
ATP-grasp domain/CoA-ligase, putative
— +2 more Both
LAMA_000535900 ⚠
Oxidoreductase FAD-binding domain/Oxidoreduct
— OG7
LAMA_000761200
Phosphoglucomutase/phosphomannomutase, alpha/
— Both
LAMA_000589700
Protein phosphatase 2C, putative
— OG6
LAMA_000574400
Ribose/Galactose Isomerase, putative
— Both
LAMA_000577500
hypothetical protein, conserved
— Both
LAMA_000158600
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000346900
Proteasome subunit, putative
— Both
LAMA_000655000
Myristoyl-CoA:protein N-myristoyltransferase,
— Both
LAMA_000084900
DeoC/LacD family aldolase, putative
— Both
LAMA_000296700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730500 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000228100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000678100 ⚠
Oxidoreductase FAD-binding domain/Oxidoreduct
— OG7
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— Both
LAMA_000173100 ⚠
Oxidoreductase FAD-binding domain containing
— OG7
LAMA_000203200 ⚠
Oxidoreductase FAD-binding domain/Oxidoreduct
— OG7
LAMA_000304300 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000566900 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000569200 ⚠
Sucrose-6F-phosphate phosphohydrolase/haloaci
— OG7
LAMA_000569100 ⚠
haloacid dehalogenase-like hydrolase/Sucrose-
— OG7
LAMA_000771200 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000760700 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000767800 ⚠
ARD/ARD' family, putative
— OG7
LAMA_000387000 ⚠
ARD/ARD' family/AraC-like ligand binding doma
— OG7
LAMA_000814100
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000461400 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000739100
Uracil phosphoribosyltransferase, putative
— Both
LAMA_000425300 ⚠
Oxidoreductase FAD-binding domain/Ferric redu
— Both
LAMA_000475600
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000443600 ⚠
Thiolase, N-terminal domain/Beta-ketoacyl syn
— Both
LAMA_000503900
Phosphoribosyl transferase domain containing
— Both
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000425200 ⚠
Oxidoreductase FAD-binding domain/Oxidoreduct
— Both
LAMA_000225800 ⚠
Oxidoreductase FAD-binding domain/Ferric redu
— Both
LAMA_000352300
Protein of unknown function (DUF2870), putati
— Both
LAMA_000768100
Pyruvate kinase, barrel domain/Pyruvate kinas
— Both
LAMA_000688600
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000114700 ⚠
Choline/Carnitine o-acyltransferase, putative
— Both
LAMA_000418500
Glutamine amidotransferase class-I/Peptidase
— Both
LAMA_000691700
Enoyl-CoA hydratase/isomerase, putative
— Both
LAMA_000405000 ⚠
Phosphoribosyl transferase domain containing
— Both
LAMA_000405100 ⚠
Phosphoribosyl transferase domain containing
— Both
LAMA_000730600 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000249200
Transaldolase/Fructose-6-phosphate aldolase,
— Both
LAMA_000475100
Transketolase, thiamine diphosphate binding d
— Both
LAMA_000462300
Triosephosphate isomerase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.