LAMA_000158600

Protein kinase domain/Protein tyrosine kinase/Lipopolysaccharide kinase (Kdo/WaaP) family/Haspin like kinase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147455 OG7: OG7_0000396 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000311100 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000273900
GHMP kinases N terminal domain/Mevalonate 5-d
— OG6
LAMA_000691700
Enoyl-CoA hydratase/isomerase, putative
— OG6
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000695600
hypothetical protein, conserved
— OG6
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000125300
UBA-like domain containing protein, putative
— OG6
LAMA_000014700
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LAMA_000611100
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000566800
haloacid dehalogenase-like hydrolase/Sucrose-
— OG6
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— OG6
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— OG6
LAMA_000633000
Biotin/lipoate A/B protein ligase family, put
— OG6
LAMA_000114700
Choline/Carnitine o-acyltransferase, putative
— OG6
LAMA_000663300
Alpha/beta hydrolase family/Serine aminopepti
— OG6
LAMA_000552500
50S ribosome-binding GTPase/Protein of unknow
— OG6
LAMA_000665300
Importin-beta N-terminal domain/Exportin 1-li
— OG6
LAMA_000498600
hypothetical protein, conserved
— OG6
LAMA_000761200
Phosphoglucomutase/phosphomannomutase, alpha/
— OG6
LAMA_000306300 ⚠
Tetratricopeptide repeat, putative
— OG6
LAMA_000553400 ⚠
Tetratricopeptide repeat/Potential Monad-bind
— OG6
LAMA_000675300 ⚠
Cytidylyltransferase-like, putative
— OG6
LAMA_000566200
WD domain, G-beta repeat, putative
— OG6
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— OG6
LAMA_000311700
Elongation factor Tu GTP binding domain/Elong
— OG6
LAMA_000346900
Proteasome subunit, putative
— OG6
LAMA_000589700
Protein phosphatase 2C, putative
— OG6
LAMA_000552400 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000681300 ⚠
Iron/manganese superoxide dismutases, alpha-h
— OG6
LAMA_000183800
PITH domain containing protein, putative
— OG6
LAMA_000283100
UTP--glucose-1-phosphate uridylyltransferase,
— OG6
LAMA_000133600
hypothetical protein, conserved
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000084900
DeoC/LacD family aldolase, putative
— OG6
LAMA_000724400
Transcription factor S-II (TFIIS), putative
— OG6
LAMA_000555200
hypothetical protein, conserved
— OG6
LAMA_000705000
Nicotinate phosphoribosyltransferase (NAPRTas
— OG6
LAMA_000535800
UBA/TS-N domain containing protein, putative
— OG6
LAMA_000734700
Soluble NSF attachment protein, SNAP, putativ
— OG6
LAMA_000624300
Ubiquitin family/Ubiquitin carboxyl-terminal
— OG6
LAMA_000247200
Amidohydrolase family, putative
— OG6
LAMA_000368700
Sucrase/ferredoxin-like, putative
— OG6
LAMA_000566500
Electron transfer flavoprotein domain/Electro
— OG6
LAMA_000453000
Alanine racemase, N-terminal domain containin
— OG6
LAMA_000420700
SEP domain containing protein, putative
— OG6
LAMA_000671000 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000575600
Telomere recombination/Putative GTP-binding c
— OG6
LAMA_000241800
Phytanoyl-CoA dioxygenase (PhyH)/2OG-Fe(II) o
— OG6
LAMA_000655000
Myristoyl-CoA:protein N-myristoyltransferase,
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.