LAMA_000280100

Citrate synthase, C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101425 OG7: OG7_0003359 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000189200
Phosphoglucose isomerase, putative
— Both
LAMA_000118100 ⚠
DinB superfamily/Sulfatase-modifying factor e
— Both
LAMA_000622300 ⚠
Protein of unknown function (DUF3808), putati
— Both
LAMA_000679200 ⚠
16S rRNA methyltransferase RsmB/F, putative
— Both
LAMA_000773900
hypothetical protein, conserved
— Both
LAMA_000440100
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LAMA_000645300
Haloacid dehalogenase-like hydrolase/HAD-hyro
— Both
LAMA_000377600
hypothetical protein, conserved
— Both
LAMA_000390500
Nucleosome assembly protein (NAP), putative
— Both
LAMA_000190100
Aminotransferase class I and II, putative
— Both
LAMA_000276700
hypothetical protein, conserved
— Both
LAMA_000383500
CTP synthase N-terminus/Glutamine amidotransf
— Both
LAMA_000572100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000743400 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LAMA_000624900 ⚠
N-terminal domain of 16S rRNA methyltransfera
— OG7
LAMA_000493100 ⚠
PUA domain/16S rRNA methyltransferase RsmB/F,
— OG7
LAMA_000521400 ⚠
Methyltransferase domain containing protein,
— OG7
LAMA_000108400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000461500 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000475600
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000278000
Aconitase family (aconitate hydratase)/Aconit
— Both
LAMA_000797400
FGGY family of carbohydrate kinases, N-termin
— Both
LAMA_000523600
Aminotransferase class-V/Cys/Met metabolism P
— Both
LAMA_000246900
Aspartate/ornithine carbamoyltransferase, car
— Both
LAMA_000617400
Hydroxymethylglutaryl-coenzyme A reductase, p
— Both
LAMA_000456800 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— Both
LAMA_000800100
Shikimate / quinate 5-dehydrogenase/3-hydroxy
— Both
LAMA_000342600 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000461400 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000070400
Phosphorylase superfamily, putative
— Both
LAMA_000221800
Enolase, N-terminal domain/Enolase, C-termina
— Both
LAMA_000109000 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— Both
LAMA_000212500
von Willebrand factor type A domain containin
— Both
LAMA_000013900
D-isomer specific 2-hydroxyacid dehydrogenase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.