LAMA_000244400

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102356 OG7: OG7_0007343 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000784400
Proteasome complex subunit Rpn13 ubiquitin re
— Both
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000213000 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000458300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000562800 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000512800 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000036700
26S proteasome regulatory subunit RPN6 N-term
— Both
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000172800 ⚠
Proteasome subunit A N-terminal signature/Pro
— +1 more Both
LAMA_000236800
Cyclic nucleotide-binding domain/PAS fold/Pro
— OG6
LAMA_000803800
hypothetical protein, conserved
— Both
LAMA_000541800 ⚠
TCP-1/cpn60 chaperonin family, putative
— +5 more Both
LAMA_000435100
hypothetical protein, conserved
— Both
LAMA_000688200 ⚠
TCP-1/cpn60 chaperonin family, putative
— +5 more Both
LAMA_000657400
hypothetical protein, conserved
— Both
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000571200 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000321000 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000380400 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000303100 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000576500 ⚠
Galactose oxidase, central domain containing
— OG7
LAMA_000495500
hypothetical protein, conserved
— OG7
LAMA_000506300 ⚠
Nucleotidyltransferase domain/RNA editing 3'
— OG7
LAMA_000540500
Tetratricopeptide repeat/TPR repeat, putative
— Both
LAMA_000498900 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000368600 ⚠
Kelch motif containing protein, putative
— OG7
LAMA_000475400 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000322400 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000416900 ⚠
Proteasome subunit A N-terminal signature/Pro
— OG7
LAMA_000242200 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAMA_000020200
PCI domain/Proteasome regulatory subunit C-te
— Both
LAMA_000300200
PCI domain containing protein, putative
— Both
LAMA_000127500
RPN1/RPN2 N-terminal domain/Proteasome/cyclos
— Both
LAMA_000350900
Proteasomal ATPase OB C-terminal domain/Holli
— OG6
LAMA_000735800
JAB1/Mov34/MPN/PAD-1 ubiquitin protease/Proka
— Both
LAMA_000403400
PCI domain/26S proteasome regulatory subunit
— Both
LAMA_000423400
Proteasomal ATPase OB C-terminal domain/ATPas
— OG6
LAMA_000572000
HEAT repeats/26S proteasome regulatory subuni
— Both
LAMA_000666300
CSN8/PSMD8/EIF3K family, putative
— Both
LAMA_000045600
Proteasomal ATPase OB C-terminal domain/Holli
— OG6
LAMA_000683300
26S proteasome subunit RPN7/PCI domain contai
— Both
LAMA_000658200
JAB1/Mov34/MPN/PAD-1 ubiquitin protease/Maint
— Both
LAMA_000422900
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000684900 ⚠
Phosducin/Thioredoxin, putative
— Both
LAMA_000551000 ⚠
Phosducin/Thioredoxin, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.