LAMA_000093300

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_478677 OG7: OG7_0293510 187 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 187 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000356900
hypothetical protein, conserved
— Both
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— Both
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000681500 ⚠
SpoU rRNA Methylase family, putative
— Both
LAMA_000602700
CLASP N terminal, putative
— Both
LAMA_000167100
MIF4G domain containing protein, putative
— Both
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000231100
hypothetical protein, conserved
— Both
LAMA_000174100
hypothetical protein, conserved
— Both
LAMA_000405800
Domain of unknown function (DUF4042), putativ
— Both
LAMA_000278600
Flagellar-associated PapD-like, putative
— Both
LAMA_000215700
WD domain, G-beta repeat, putative
— Both
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000684700 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000815700 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000554400 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000608200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000815500 ⚠
MCM OB domain/MCM P-loop domain/MCM AAA-lid d
— OG7
LAMA_000385200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAMA_000149100 ⚠
Ubiquitin-2 like Rad60 SUMO-like/Ubiquitin fa
— OG7
LAMA_000065200 ⚠
MCM OB domain/MCM P-loop domain/AAA domain (d
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000142100 ⚠
MCM N-terminal domain/MCM OB domain/MCM P-loo
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.