LAMA_000304500

IMP dehydrogenase / GMP reductase domain/CBS domain/FMN-dependent dehydrogenase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100534 OG7: OG7_0002926 79 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 79 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000255500 ⚠
EMG1/NEP1 methyltransferase, putative
— OG6
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000661700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000537000 ⚠
hypothetical protein, conserved
— OG6
LAMA_000283700 ⚠
Hydantoinase/oxoprolinase N-terminal region/H
— Both
LAMA_000012800 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
LAMA_000178900 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000247300 ⚠
Carbamoyl-phosphate synthase small chain, CPS
— Both
LAMA_000022400 ⚠
ATP synthase alpha/beta family, beta-barrel d
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000648200 ⚠
HI0933-like protein/Pyridine nucleotide-disul
— Both
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000779800 ⚠
hypothetical protein, conserved
— OG6
LAMA_000768300 ⚠
Transketolase, pyrimidine binding domain/Tran
— Both
LAMA_000778000 ⚠
KRI1-like family/KRI1-like family C-terminal,
— OG6
LAMA_000005200 ⚠
Carboxyl transferase domain containing protei
— Both
LAMA_000592300 ⚠
Ribosome biogenesis regulatory protein (RRS1)
— OG6
LAMA_000784900 ⚠
Eukaryotic rRNA processing protein EBP2, puta
— OG6
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000648100 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000718200
hypothetical protein, conserved
— OG7
LAMA_000336300 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000490200 ⚠
ATP synthase alpha/beta family, beta-barrel d
— Both
LAMA_000082800
hypothetical protein, conserved
— OG7
LAMA_000152700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000626300 ⚠
hypothetical protein
— OG7
LAMA_000763900 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— Both
LAMA_000602700 ⚠
CLASP N terminal, putative
— Both
LAMA_000104800 ⚠
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000643700 ⚠
hypothetical protein, conserved
— Both
LAMA_000798700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LAMA_000439600 ⚠
Glycogen recognition site of AMP-activated pr
— Both
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— Both
LAMA_000516300 ⚠
Prenyltransferase and squalene oxidase repeat
— Both
LAMA_000111300 ⚠
MORN repeat, putative
— Both
LAMA_000510100 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.