LAMA_000247300

Carbamoyl-phosphate synthase small chain, CPSase domain/Glutamine amidotransferase class-I/Peptidase C26/Carbamoyl-phosphate synthase L chain, ATP binding domain/ATP-grasp domain/Carbamoyl-phosphate synthetase large chain, oligomerisation domain/D-ala D-ala ligase C-terminus/MGS-like domain/Arginosuccinate synthase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100435 OG7: OG7_0002358 12 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 12 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000297500
Putative TPR-like repeat/Anaphase-promoting c
— Both
LAMA_000005200
Carboxyl transferase domain containing protei
— Both
LAMA_000751700
RNA-binding signal recognition particle 68, p
— Both
LAMA_000768300
Transketolase, pyrimidine binding domain/Tran
— Both
LAMA_000266300 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— Both
LAMA_000412200
Dehydrogenase E1 component, putative
— Both
LAMA_000011200
ATP synthase, Delta/Epsilon chain, beta-sandw
— Both
LAMA_000648200 ⚠
HI0933-like protein/Pyridine nucleotide-disul
— Both
LAMA_000063800
Biotin-requiring enzyme/e3 binding domain/2-o
— Both
LAMA_000110500 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000648100 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.