LAMA_000721900

M17 aminopeptidase N-terminal domain 2/Cytosol aminopeptidase family, catalytic domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_105603 OG7: OG7_0003405 259 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 259 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— +7 more Both
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— +7 more Both
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000347500 ⚠
hypothetical protein, conserved
— +2 more Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000593700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000559100 ⚠
RNB domain containing protein, putative
— +1 more Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— +1 more Both
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— +1 more Both
LAMA_000179200 ⚠
PUB domain containing protein, putative
— OG7
LAMA_000703300 ⚠
Cyclin/Cyclin, N-terminal domain containing p
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000158500 ⚠
MORN repeat, putative
— OG7
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000269000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000178900 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000516300 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000111300 ⚠
MORN repeat, putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000052500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000279700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000573800 ⚠
p21-C-terminal region-binding protein, putati
— OG7
LAMA_000794200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000107800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000159500 ⚠
Exonuclease, putative
— OG7
LAMA_000800400 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.