LAMA_000557900

Rrp44-like cold shock domain/Dis3-like cold-shock domain 2 (CSD2)/RNB domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101226 OG7: OG7_0002439 228 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 228 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— +1 more Both
LAMA_000232500 ⚠
hypothetical protein, conserved
— Both
LAMA_000812000 ⚠
SET domain containing protein, putative
— Both
LAMA_000008100 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— +1 more Both
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— +1 more Both
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— +2 more Both
LAMA_000487100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000108800 ⚠
hypothetical protein
— OG7
LAMA_000395000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000532300 ⚠
hypothetical protein
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000279900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000112500 ⚠
XPC-binding domain/UBA/TS-N domain containing
— OG7
LAMA_000055200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000284300 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000274600 ⚠
Galactose mutarotase-like/Glycosyl hydrolases
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000273400 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000611000 ⚠
Formate--tetrahydrofolate ligase, putative
— OG7
LAMA_000592400 ⚠
Histidyl-tRNA synthetase/Anticodon binding do
— OG7
LAMA_000367500 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000696200 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000760900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000771900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000793100 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000597400 ⚠
Armadillo/beta-catenin-like repeat/Atypical A
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000502500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000479800 ⚠
Metallo-beta-lactamase superfamily domain/Cle
— OG7
LAMA_000435400 ⚠
MobA-like NTP transferase domain/Nucleotidyl
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000713100 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000766400 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
LAMA_000616800 ⚠
tRNA synthetases class I (I, L, M and V)/tRNA
— OG7
LAMA_000499400 ⚠
Translation initiation factor eIF3 subunit, p
— OG7
LAMA_000532400 ⚠
Nucleoporin autopeptidase/Nuclear protein 96,
— OG7
LAMA_000367600 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000401100 ⚠
La domain containing protein, putative
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000757200 ⚠
Metallo-beta-lactamase superfamily/Metallo-be
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000593200 ⚠
GrpE, putative
— OG7
LAMA_000781300 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000771800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000593300 ⚠
GrpE, putative
— OG7
LAMA_000564200 ⚠
ATP cone domain/Ribonucleotide reductase, all
— OG7
LAMA_000044900 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.