LAMA_000593300

GrpE, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_188614 OG7: OG7_0004892 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000103100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000576700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000544900 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
LAMA_000069000 ⚠
Sperm-tail PG-rich repeat, putative
— OG7
LAMA_000418900 ⚠
BAG domain containing protein, putative
— OG7
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— OG7
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— OG7
LAMA_000564200 ⚠
ATP cone domain/Ribonucleotide reductase, all
— OG7
LAMA_000225700 ⚠
SLOG cluster4 family/Possible lysine decarbox
— OG7
LAMA_000388500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000592800 ⚠
CS domain containing protein, putative
— OG7
LAMA_000542600 ⚠
Arginyl tRNA synthetase N terminal domain/tRN
— OG7
LAMA_000228400 ⚠
OB-fold nucleic acid binding domain/Replicati
— OG7
LAMA_000491300 ⚠
GIY-YIG catalytic domain containing protein,
— OG7
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— OG7
LAMA_000666600 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000233800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000706800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000271100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000105400 ⚠
Variant UBP zinc finger/Zn-finger in ubiquiti
— OG7
LAMA_000223300 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000268400 ⚠
Mak10 subunit, NatC N(alpha)-terminal acetylt
— OG7
LAMA_000284400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000578700 ⚠
Serine hydroxymethyltransferase, putative
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000109100 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAMA_000125400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000738900 ⚠
N2227-like protein, putative
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— OG7
LAMA_000619800 ⚠
T-complex protein 11, putative
— OG7
LAMA_000347500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000050400 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000404000 ⚠
tRNA synthetases class I (I, L, M and V)/tRNA
— OG7
LAMA_000719500 ⚠
MYND finger containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.