LAMA_000050400

3'5'-cyclic nucleotide phosphodiesterase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146459 OG7: OG7_0042785 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000233800
hypothetical protein, conserved
— Both
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000593200 ⚠
GrpE, putative
— Both
LAMA_000576700
hypothetical protein, conserved
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000738900
N2227-like protein, putative
— Both
LAMA_000043900
Protein tyrosine kinase/Protein kinase domain
— Both
LAMA_000177100
Anion-transporting ATPase/AAA domain containi
— Both
LAMA_000069000
Sperm-tail PG-rich repeat, putative
— Both
LAMA_000612600
Tetratricopeptide repeat/TPR repeat, putative
— OG6
LAMA_000619800
T-complex protein 11, putative
— Both
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— Both
LAMA_000442500 ⚠
ThiF family/Ubiquitin-activating enzyme activ
— Both
LAMA_000271100
hypothetical protein, conserved
— Both
LAMA_000105400
Variant UBP zinc finger/Zn-finger in ubiquiti
— Both
LAMA_000228400
OB-fold nucleic acid binding domain/Replicati
— Both
LAMA_000290700
Fibrillarin/tRNA methyltransferase complex GC
— Both
LAMA_000231100
hypothetical protein, conserved
— Both
LAMA_000262000
hypothetical protein, conserved
— Both
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000125400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000572400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000669800 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAMA_000593300 ⚠
GrpE, putative
— OG7
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000020900 ⚠
WD domain, G-beta repeat/WD40-like Beta Prope
— OG7
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000109100
Protein prenyltransferase alpha subunit repea
— Both
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000167100
MIF4G domain containing protein, putative
— Both
LAMA_000726100
hypothetical protein, conserved
— Both
LAMA_000101800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000136800
hypothetical protein, conserved
— Both
LAMA_000235200
HEAT repeat, putative
— Both
LAMA_000522500
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.