LAMA_000236100

Bacterial NAD-glutamate dehydrogenase/Glutamate/Leucine/Phenylalanine/Valine dehydrogenase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_106160 OG7: OG7_0011174 114 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 114 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +1 more OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +6 more Both
LAMA_000114700 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000618800
MORN repeat, putative
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000608600
SET domain containing protein, putative
— Both
LAMA_000670900
hypothetical protein, conserved
— Both
LAMA_000093300
hypothetical protein, conserved
— Both
LAMA_000346000
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
LAMA_000073300 ⚠
MORN repeat, putative
— Both
LAMA_000149800
hypothetical protein, conserved
— Both
LAMA_000152700 ⚠
hypothetical protein, conserved
— Both
LAMA_000136800
hypothetical protein, conserved
— Both
LAMA_000662900
PheRS DNA binding domain 1/PheRS DNA binding
— Both
LAMA_000797400
FGGY family of carbohydrate kinases, N-termin
— Both
LAMA_000193700
WD domain, G-beta repeat, putative
— Both
LAMA_000434700
AhpC/TSA family/Redoxin/C-terminal domain of
— Both
LAMA_000456800 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000109000 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000235200
HEAT repeat, putative
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000781200
TGS domain/Threonyl and Alanyl tRNA synthetas
— Both
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000268400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000039500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000304300 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
LAMA_000351000 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000020900 ⚠
WD domain, G-beta repeat/WD40-like Beta Prope
— OG7
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000748200 ⚠
Elongation factor Tu GTP binding domain conta
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000791100 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000763200 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000420600 ⚠
Choline/Carnitine o-acyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.