LAMA_000120800

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase/Hsp90 protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100204 OG7: OG7_0001978 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000278400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000448200 ⚠
Domain of unknown function (DUF1899)/Type of
— +4 more Both
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— +6 more Both
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +4 more OG7
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— +3 more Both
LAMA_000673600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000237100 ⚠
DnaJ domain/DnaJ C terminal domain containing
— OG7
LAMA_000057700 ⚠
Transmembrane Fragile-X-F protein, putative
— OG7
LAMA_000688500 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000796400 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000418200 ⚠
DnaJ C terminal domain/DnaJ central domain co
— OG7
LAMA_000327800 ⚠
DnaJ domain/Domain of unknown function (DUF19
— OG7
LAMA_000400400 ⚠
DnaJ domain/DnaJ C terminal domain/DnaJ centr
— OG7
LAMA_000706800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000171700 ⚠
NIF3 (NGG1p interacting factor 3), putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000462000 ⚠
SacI homology domain/Protein of unknown funct
— OG7
LAMA_000808900 ⚠
SacI homology domain containing protein, puta
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000748200 ⚠
Elongation factor Tu GTP binding domain conta
— OG7
LAMA_000663800 ⚠
Staphylococcal nuclease homologue/Tudor domai
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000781300 ⚠
Tetratricopeptide repeat, putative
— OG7
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— OG7
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— OG7
LAMA_000418900 ⚠
BAG domain containing protein, putative
— OG7
LAMA_000328500 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000564200 ⚠
ATP cone domain/Ribonucleotide reductase, all
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000771800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000362300 ⚠
Adenylate cyclase associated (CAP) N terminal
— OG7
LAMA_000214300 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LAMA_000542600 ⚠
Arginyl tRNA synthetase N terminal domain/tRN
— OG7
LAMA_000270000 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.