LAMA_000462000

SacI homology domain/Protein of unknown function, DUF547, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101803 OG7: OG7_0000974 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000088500 ⚠
Sec7 domain containing protein, putative
— Both
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LAMA_000092600
Dynein heavy chain, N-terminal region 2, puta
— OG6
LAMA_000410200 ⚠
hypothetical protein, conserved
— Both
LAMA_000512800 ⚠
Axonemal dynein light chain, putative
— Both
LAMA_000713800 ⚠
hypothetical protein, conserved
— Both
LAMA_000601200 ⚠
hypothetical protein, conserved
— Both
LAMA_000710500 ⚠
hypothetical protein, conserved
— Both
LAMA_000120100 ⚠
hypothetical protein, conserved
— Both
LAMA_000624200 ⚠
hypothetical protein, conserved
— Both
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LAMA_000783300 ⚠
hypothetical protein, conserved
— Both
LAMA_000793400 ⚠
hypothetical protein, conserved
— Both
LAMA_000442100 ⚠
Galactose oxidase, central domain containing
— Both
LAMA_000218600 ⚠
hypothetical protein, conserved
— Both
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— Both
LAMA_000270100 ⚠
WW domain containing protein, putative
— Both
LAMA_000270200 ⚠
hypothetical protein, conserved
— Both
LAMA_000180000 ⚠
HIT zinc finger containing protein, putative
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000593700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747800 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000749000 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000800400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000538200 ⚠
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG7
LAMA_000747200 ⚠
Uncharacterized conserved protein H4 (DUF2046
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— OG7
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000276300 ⚠
ATP12 chaperone protein, putative
— OG7
LAMA_000501300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000337200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000128600 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000437200 ⚠
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG7
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.