LAMA_000095800

Histidine phosphatase superfamily (branch 1), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100250 OG7: OG7_0002306 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000700500 ⚠
hypothetical protein, conserved
— Both
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000435400 ⚠
MobA-like NTP transferase domain/Nucleotidyl
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000349800 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000186300 ⚠
tRNA synthetases class I (C) catalytic domain
— OG7
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000720600 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000544700 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000120800 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000462000 ⚠
SacI homology domain/Protein of unknown funct
— OG7
LAMA_000437200 ⚠
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG7
LAMA_000276300 ⚠
ATP12 chaperone protein, putative
— OG7
LAMA_000785300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000070600 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000808900 ⚠
SacI homology domain containing protein, puta
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000593700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000580200 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000766500 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG7
LAMA_000714300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000416700 ⚠
ATP synthase, putative
— OG7
LAMA_000310700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
LAMA_000590600 ⚠
Eukaryotic initiation factor 4E, putative
— OG7
LAMA_000063800 ⚠
Biotin-requiring enzyme/e3 binding domain/2-o
— OG7
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000507600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.