LAMA_000349800

Protein kinase domain/Protein tyrosine kinase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_150779 OG7: OG7_0001715 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000617700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000500300 ⚠
PCI domain containing protein, putative
— OG7
LAMA_000776200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000282900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000337300 ⚠
ATP synthase (E/31 kDa) subunit, putative
— OG7
LAMA_000423700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000411500 ⚠
V-ATPase subunit H, putative
— OG7
LAMA_000285900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LAMA_000760000 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000128600 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
LAMA_000382300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747600 ⚠
Tetratricopeptide repeat/DnaJ domain containi
— OG7
LAMA_000125500 ⚠
STI1 domain containing protein, putative
— OG7
LAMA_000223400 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000310800 ⚠
DnaJ domain containing protein, putative
— OG7
LAMA_000360600 ⚠
Splicing factor 1 helix-hairpin domain/KH dom
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000152700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000579400 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000636000 ⚠
SPRY domain containing protein, putative
— OG7
LAMA_000726000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000423100 ⚠
tRNA-methyltransferase O, putative
— OG7
LAMA_000070600 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000310700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000412200 ⚠
Dehydrogenase E1 component, putative
— OG7
LAMA_000598500 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000278400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000525000 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000725700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000274400 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
LAMA_000725600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000202000 ⚠
N2,N2-dimethylguanosine tRNA methyltransferas
— OG7
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.