LAMA_000796000

Leucine carboxyl methyltransferase/Cupin-like domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_106314 OG7: OG7_0005126 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000700500 ⚠
hypothetical protein, conserved
— Both
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000564700 ⚠
short chain dehydrogenase/Enoyl-(Acyl carrier
— Both
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— Both
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— Both
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— Both
LAMA_000202000 ⚠
N2,N2-dimethylguanosine tRNA methyltransferas
— Both
LAMA_000076700 ⚠
hypothetical protein, conserved
— Both
LAMA_000053500 ⚠
hypothetical protein, conserved
— Both
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
LAMA_000082800 ⚠
hypothetical protein, conserved
— Both
LAMA_000451500 ⚠
Inositol hexakisphosphate, putative
— Both
LAMA_000423700 ⚠
hypothetical protein, conserved
— Both
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000598500 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— Both
LAMA_000582600 ⚠
Uncharacterized ACR, COG1678, putative
— Both
LAMA_000800300 ⚠
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000362800 ⚠
hypothetical protein, conserved
— Both
LAMA_000364000 ⚠
Rab3 GTPase-activating protein regulatory sub
— Both
LAMA_000306900 ⚠
PUB domain containing protein, putative
— Both
LAMA_000353700 ⚠
hypothetical protein, conserved
— Both
LAMA_000310700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000636000 ⚠
SPRY domain containing protein, putative
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000714300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000070600 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000785300 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000349800 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000299200 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000600500 ⚠
tRNA pseudouridine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.