LAMA_000364000

Rab3 GTPase-activating protein regulatory subunit N-terminus, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_148307 OG7: OG7_0044573 95 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 95 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000432500
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000619900 ⚠
Temperature dependent protein affecting M2 ds
— Both
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000101800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000203800 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000491200 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000082800
hypothetical protein, conserved
— Both
LAMA_000020900 ⚠
WD domain, G-beta repeat/WD40-like Beta Prope
— OG7
LAMA_000451500
Inositol hexakisphosphate, putative
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000235200
HEAT repeat, putative
— Both
LAMA_000788400
hypothetical protein, conserved
— Both
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000368300
hypothetical protein, conserved
— Both
LAMA_000136800
hypothetical protein, conserved
— Both
LAMA_000152700 ⚠
hypothetical protein, conserved
— Both
LAMA_000160100
hypothetical protein, conserved
— Both
LAMA_000582600
Uncharacterized ACR, COG1678, putative
— Both
LAMA_000171800 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000755700 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000152600 ⚠
Skp1 family, dimerisation domain containing p
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000745100 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000157600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000378300 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000743600
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000776700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000669600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000116600 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000816500 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000355200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000463700 ⚠
Rad17 P-loop domain/ATPase family associated
— OG7
LAMA_000045700
hypothetical protein, conserved
— Both
LAMA_000055700
DENN (AEX-3) domain containing protein, putat
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.