LAMA_000306400

Leucine carboxyl methyltransferase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100931 OG7: OG7_0005126 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000700500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000505500 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeats (m
— OG7
LAMA_000307100 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095800 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000095700 ⚠
6-phosphofructo-2-kinase, putative
— OG7
LAMA_000564700 ⚠
short chain dehydrogenase/Enoyl-(Acyl carrier
— OG7
LAMA_000423700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000451500 ⚠
Inositol hexakisphosphate, putative
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000800300 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
LAMA_000063500 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000507400 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000362800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000776200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000349600 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000364000 ⚠
Rab3 GTPase-activating protein regulatory sub
— OG7
LAMA_000306900 ⚠
PUB domain containing protein, putative
— OG7
LAMA_000353700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000587200 ⚠
Leucine Rich repeat/Leucine Rich Repeat, puta
— OG7
LAMA_000125800 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAMA_000227200 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000337300 ⚠
ATP synthase (E/31 kDa) subunit, putative
— OG7
LAMA_000411500 ⚠
V-ATPase subunit H, putative
— OG7
LAMA_000220700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000415500 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000579400 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000295800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000563400 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000656200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000582600 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LAMA_000636000 ⚠
SPRY domain containing protein, putative
— OG7
LAMA_000197000 ⚠
Lipase (class 3), putative
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000018000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000466400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000360600 ⚠
Splicing factor 1 helix-hairpin domain/KH dom
— OG7
LAMA_000076700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000078900 ⚠
Glutamine synthetase, beta-Grasp domain/Gluta
— OG7
LAMA_000617700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000760000 ⚠
ATP synthase alpha/beta family, beta-barrel d
— OG7
LAMA_000207500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000682400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000456600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000043700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.