LAMA_000456600

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_156990 OG7: OG7_0007247 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000582600
Uncharacterized ACR, COG1678, putative
— Both
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000389300 ⚠
hypothetical protein
— OG6
LAMA_000389400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000054400 ⚠
Domain of unknown function (DUF1935)/Calpain
— OG6
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000451500
Inositol hexakisphosphate, putative
— Both
LAMA_000082800
hypothetical protein, conserved
— Both
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000253200
hypothetical protein, conserved
— Both
LAMA_000306400 ⚠
Leucine carboxyl methyltransferase, putative
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000564400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000715800 ⚠
Pentacotripeptide-repeat region of PRORP/Prot
— OG7
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000467600 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000043700
hypothetical protein, conserved
— Both
LAMA_000745800 ⚠
Endonuclease/Exonuclease/phosphatase family,
— Both
LAMA_000817400 ⚠
Protein-only RNase P, putative
— Both
LAMA_000430000 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000700800
hypothetical protein, conserved
— Both
LAMA_000295800
hypothetical protein, conserved
— Both
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— Both
LAMA_000612500
Stabilization of polarity axis, putative
— Both
LAMA_000362800 ⚠
hypothetical protein, conserved
— Both
LAMA_000466400
hypothetical protein, conserved
— Both
LAMA_000364000
Rab3 GTPase-activating protein regulatory sub
— Both
LAMA_000465900
hypothetical protein, conserved
— Both
LAMA_000796000 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAMA_000563400 ⚠
'Cold-shock' DNA-binding domain containing pr
— Both
LAMA_000548100
Protein tyrosine kinase/Kinase-like/Protein k
— OG6
LAMA_000045700
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.