LAMA_000432500

DEAD/DEAH box helicase/AAA domain/Helicase conserved C-terminal domain/Helicase associated domain (HA2), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_126543 OG7: OG7_0000698 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000445700
hypothetical protein, conserved
— OG6
LAMA_000697700
WD domain, G-beta repeat, putative
— OG6
LAMA_000496800
Not1 N-terminal domain, CCR4-Not complex comp
— OG6
LAMA_000368300
hypothetical protein, conserved
— OG6
LAMA_000743500
hypothetical protein, conserved
— OG6
LAMA_000101800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000492300
Clusterin-associated protein-1, putative
— OG6
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG6
LAMA_000115500
Sec23-binding domain of Sec16, putative
— OG6
LAMA_000710500
hypothetical protein, conserved
— OG6
LAMA_000619900
Temperature dependent protein affecting M2 ds
— OG6
LAMA_000668900
Microtubule-binding protein MIP-T3 CH-like do
— OG6
LAMA_000582600
Uncharacterized ACR, COG1678, putative
— OG6
LAMA_000315700
hypothetical protein, conserved
— OG6
LAMA_000512800
Axonemal dynein light chain, putative
— OG6
LAMA_000784000
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000609800
hypothetical protein, conserved
— OG6
LAMA_000331000
hypothetical protein, conserved
— OG6
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG6
LAMA_000067600
Zinc finger, C3HC4 type (RING finger)/Ring fi
— OG6
LAMA_000183700
Initiation factor 2 subunit family, putative
— OG6
LAMA_000235200
HEAT repeat, putative
— OG6
LAMA_000660800
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000076700
hypothetical protein, conserved
— OG6
LAMA_000153100
ATPase family associated with various cellula
— OG6
LAMA_000422900
AAA domain (dynein-related subfamily)/AAA dom
— OG6
LAMA_000053500
hypothetical protein, conserved
— OG6
LAMA_000370200
Concanavalin A-like lectin/glucanases superfa
— OG6
LAMA_000116000
hypothetical protein, conserved
— OG6
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— OG6
LAMA_000474000
hypothetical protein, conserved
— OG6
LAMA_000117800
Kinesin motor domain/Microtubule binding, put
— OG6
LAMA_000612500
Stabilization of polarity axis, putative
— OG6
LAMA_000248900
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000721800
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000362800
hypothetical protein, conserved
— OG6
LAMA_000725800
hypothetical protein, conserved
— OG6
LAMA_000657400
hypothetical protein, conserved
— OG6
LAMA_000732300
WD domain, G-beta repeat, putative
— OG6
LAMA_000556900
hypothetical protein, conserved
— OG6
LAMA_000364000
Rab3 GTPase-activating protein regulatory sub
— OG6
LAMA_000586100
MATH domain containing protein, putative
— OG6
LAMA_000520700
hypothetical protein, conserved
— OG6
LAMA_000591000
hypothetical protein, conserved
— OG6
LAMA_000071400
Paraflagellar rod protein, putative
— OG6
LAMA_000090400
HECT-domain (ubiquitin-transferase), putative
— OG6
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG6
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG6
LAMA_000149400
Fibronectin-binding protein A N-terminus (Fbp
— OG6
LAMA_000298400 ⚠
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.