LAMA_000609800

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147272 OG7: OG7_0043245 163 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 163 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000019300 ⚠
Cullin family, putative
— Both
LAMA_000136800
hypothetical protein, conserved
— Both
LAMA_000536900
Right handed beta helix region/Periplasmic co
— Both
LAMA_000215700
WD domain, G-beta repeat, putative
— Both
LAMA_000232600
hypothetical protein, conserved
— Both
LAMA_000248900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000067600 ⚠
Zinc finger, C3HC4 type (RING finger)/Ring fi
— Both
LAMA_000235200
HEAT repeat, putative
— Both
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— Both
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000432500
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000053500
hypothetical protein, conserved
— Both
LAMA_000491200 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000203800 ⚠
RNA polymerases N / 8 kDa subunit, putative
— Both
LAMA_000101800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000076700
hypothetical protein, conserved
— Both
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000661800 ⚠
Cyclin, N-terminal domain containing protein,
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000020900 ⚠
WD domain, G-beta repeat/WD40-like Beta Prope
— OG7
LAMA_000404100 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAMA_000459900 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000399200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000598200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000378400 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000463700 ⚠
Rad17 P-loop domain/ATPase family associated
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000668200 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.