LAMA_000784000

Protein kinase domain/Protein tyrosine kinase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100821 OG7: OG7_0000396 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000018100
Casein kinase II regulatory subunit, putative
— OG6
LAMA_000798700
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000179200
PUB domain containing protein, putative
— OG6
LAMA_000152700
hypothetical protein, conserved
— OG6
LAMA_000582600
Uncharacterized ACR, COG1678, putative
— OG6
LAMA_000149800
hypothetical protein, conserved
— OG6
LAMA_000285400
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG6
LAMA_000237800
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000319800
Cell division protein 48 (CDC48), N-terminal
— OG6
LAMA_000800300
Putative death-receptor fusion protein (DUF24
— OG6
LAMA_000132900
WD domain, G-beta repeat, putative
— OG6
LAMA_000362800
hypothetical protein, conserved
— OG6
LAMA_000364000
Rab3 GTPase-activating protein regulatory sub
— OG6
LAMA_000368300
hypothetical protein, conserved
— OG6
LAMA_000794200
IQ calmodulin-binding motif containing protei
— OG6
LAMA_000315700
hypothetical protein, conserved
— OG6
LAMA_000331000
hypothetical protein, conserved
— OG6
LAMA_000093300
hypothetical protein, conserved
— OG6
LAMA_000283700
Hydantoinase/oxoprolinase N-terminal region/H
— OG6
LAMA_000619900
Temperature dependent protein affecting M2 ds
— OG6
LAMA_000076700
hypothetical protein, conserved
— OG6
LAMA_000101800
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000053500
hypothetical protein, conserved
— OG6
LAMA_000723700
Elongation factor Tu GTP binding domain/50S r
— OG6
LAMA_000432500
DEAD/DEAH box helicase/AAA domain/Helicase co
— OG6
LAMA_000067600
Zinc finger, C3HC4 type (RING finger)/Ring fi
— OG6
LAMA_000235200
HEAT repeat, putative
— OG6
LAMA_000747000
Glutaminyl-tRNA synthetase, non-specific RNA
— OG6
LAMA_000248900
Ubiquitin carboxyl-terminal hydrolase, putati
— OG6
LAMA_000012800
Soluble NSF attachment protein, SNAP, putativ
— OG6
LAMA_000573800
p21-C-terminal region-binding protein, putati
— OG6
LAMA_000178900
Leucine Rich repeat, putative
— OG6
LAMA_000418000
NF-X1 type zinc finger/R3H domain containing
— OG6
LAMA_000111300
MORN repeat, putative
— OG6
LAMA_000136800
hypothetical protein, conserved
— OG6
LAMA_000013500
M17 aminopeptidase N-terminal domain 2, putat
— OG6
LAMA_000039800
Nop14-like family, putative
— OG6
LAMA_000591800
hypothetical protein, conserved
— OG6
LAMA_000609800
hypothetical protein, conserved
— OG6
LAMA_000304500 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000266300 ⚠
IMP dehydrogenase / GMP reductase domain/CBS
— OG6
LAMA_000199500
PSP1 C-terminal conserved region containing p
— OG6
LAMA_000516300
Prenyltransferase and squalene oxidase repeat
— OG6
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— OG6
LAMA_000149400
Fibronectin-binding protein A N-terminus (Fbp
— OG6
LAMA_000732300
WD domain, G-beta repeat, putative
— OG6
LAMA_000602700
CLASP N terminal, putative
— OG6
LAMA_000203400
hypothetical protein, conserved
— OG6
LAMA_000167100
MIF4G domain containing protein, putative
— OG6
LAMA_000405800
Domain of unknown function (DUF4042), putativ
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.