LAMA_000032800

ThiF family, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101845 OG7: OG7_0003569 121 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 121 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000132900 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000715300 ⚠
Histone-binding protein RBBP4 or subunit C of
— OG7
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— OG7
LAMA_000699000 ⚠
MutS domain III/MutS family domain IV/MutS do
— OG7
LAMA_000798700 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG7
LAMA_000776400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000719300 ⚠
PPPDE putative peptidase domain/PUB domain/Gl
— OG7
LAMA_000437700 ⚠
hypothetical protein, conserved
— OG7
LAMA_000513400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000299500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000405800 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
LAMA_000766500 ⚠
Gar1/Naf1 RNA binding region containing prote
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000473300 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000337200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000774200 ⚠
ATP synthase subunit D, putative
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— OG7
LAMA_000158000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000063800 ⚠
Biotin-requiring enzyme/e3 binding domain/2-o
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000435400 ⚠
MobA-like NTP transferase domain/Nucleotidyl
— OG7
LAMA_000416700 ⚠
ATP synthase, putative
— OG7
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000083500 ⚠
TLD, putative
— OG7
LAMA_000044600 ⚠
TLD, putative
— OG7
LAMA_000326300 ⚠
TLD, putative
— OG7
LAMA_000159500 ⚠
Exonuclease, putative
— OG7
LAMA_000128600 ⚠
Metallopeptidase family M24/FACT complex subu
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000448200 ⚠
Domain of unknown function (DUF1899)/Type of
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.