LAMA_000538200

Acyl-CoA dehydrogenase, N-terminal domain/Acyl-CoA dehydrogenase, middle domain/Acyl-CoA dehydrogenase, C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102105 OG7: OG7_0001034 35 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 35 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000189200
Phosphoglucose isomerase, putative
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000078900
Glutamine synthetase, beta-Grasp domain/Gluta
— Both
LAMA_000475100
Transketolase, thiamine diphosphate binding d
— Both
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— Both
LAMA_000204500
Adenylosuccinate synthetase, putative
— Both
LAMA_000324100
Aldehyde dehydrogenase family, putative
— Both
LAMA_000729900
Glucose-6-phosphate dehydrogenase, NAD bindin
— Both
LAMA_000768100
Pyruvate kinase, barrel domain/Pyruvate kinas
— Both
LAMA_000042700 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000317300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000462000 ⚠
SacI homology domain/Protein of unknown funct
— OG7
LAMA_000808900 ⚠
SacI homology domain containing protein, puta
— OG7
LAMA_000741600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000237000 ⚠
Endonuclease/Exonuclease/phosphatase family/R
— OG7
LAMA_000235800
Rad9, putative
— OG7
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000211300 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000688100
Glucosamine-6-phosphate isomerases/6-phosphog
— Both
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000620700
S-adenosylmethionine synthetase, N-terminal d
— Both
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000119300
Amidohydrolase family, putative
— Both
LAMA_000503100
Glycine cleavage system P-protein, putative
— Both
LAMA_000434700
AhpC/TSA family/Redoxin/C-terminal domain of
— Both
LAMA_000288700 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000751400
hypothetical protein, conserved
— Both
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000756700
Aldose 1-epimerase, putative
— Both
LAMA_000604400 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604200 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000720000 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604300 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.