LAMA_000324100

Aldehyde dehydrogenase family, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_102015 OG7: OG7_0000704 26 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 26 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000775500 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000214400 ⚠
Cys/Met metabolism PLP-dependent enzyme, puta
— Both
LAMA_000685800 ⚠
Calcineurin-like phosphoesterase, putative
— OG6
LAMA_000582000 ⚠
Calcineurin-like phosphoesterase, putative
— OG6
LAMA_000799000 ⚠
Cys/Met metabolism PLP-dependent enzyme/DegT/
— Both
LAMA_000793800
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000729900
Glucose-6-phosphate dehydrogenase, NAD bindin
— Both
LAMA_000078900
Glutamine synthetase, beta-Grasp domain/Gluta
— Both
LAMA_000180200
Pyruvate phosphate dikinase, PEP/pyruvate bin
— Both
LAMA_000096200 ⚠
Pyridine nucleotide-disulphide oxidoreductase
— Both
LAMA_000778900 ⚠
FAD dependent oxidoreductase/Pyridine nucleot
— Both
LAMA_000435400
MobA-like NTP transferase domain/Nucleotidyl
— Both
LAMA_000456800 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
LAMA_000604300 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000720000 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604200 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000604400 ⚠
Coenzyme A transferase, putative
— Both
LAMA_000778800 ⚠
ApbE family/Alanine dehydrogenase/PNT, C-term
— Both
LAMA_000756700
Aldose 1-epimerase, putative
— Both
LAMA_000236100
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000503100
Glycine cleavage system P-protein, putative
— Both
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000346000
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
LAMA_000538200
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— Both
LAMA_000109000 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.