LAMA_000237000

Endonuclease/Exonuclease/phosphatase family/RhoGAP domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_101357 OG7: OG7_0000974 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000662900 ⚠
PheRS DNA binding domain 1/PheRS DNA binding
— OG7
LAMA_000454100 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000381200 ⚠
Mitochondrial branched-chain alpha-ketoacid d
— OG7
LAMA_000448200 ⚠
Domain of unknown function (DUF1899)/Type of
— OG7
LAMA_000031500 ⚠
Aspartyl protease/gag-polyprotein putative as
— OG7
LAMA_000218600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000407500 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000707400 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000462200 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000512800 ⚠
Axonemal dynein light chain, putative
— OG7
LAMA_000656400 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAMA_000147500 ⚠
Putative zinc finger in N-recognin (UBR box),
— OG7
LAMA_000410200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000762400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAMA_000180000 ⚠
HIT zinc finger containing protein, putative
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG7
LAMA_000774200 ⚠
ATP synthase subunit D, putative
— OG7
LAMA_000590700 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000406400 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000473300 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LAMA_000783300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000375400 ⚠
Adaptin N terminal region/HEAT repeats/non-SM
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000474600 ⚠
Tubulin folding cofactor D C terminal, putati
— OG7
LAMA_000168600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000520200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000747000 ⚠
Glutaminyl-tRNA synthetase, non-specific RNA
— OG7
LAMA_000542900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000751400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000793400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000724100 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAMA_000624200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000323700 ⚠
PH domain associated with Beige/BEACH/Beige/B
— OG7
LAMA_000120100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000710500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000601200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000713800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— OG7
LAMA_000781200 ⚠
TGS domain/Threonyl and Alanyl tRNA synthetas
— OG7
LAMA_000235800 ⚠
Rad9, putative
— OG7
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.