LAMA_000615100

Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain/Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100218 OG7: OG7_0002325 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000528900 ⚠
Queuine tRNA-ribosyltransferase, putative
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000322500 ⚠
Zinc knuckle, putative
— OG7
LAMA_000171700 ⚠
NIF3 (NGG1p interacting factor 3), putative
— OG7
LAMA_000538200 ⚠
Acyl-CoA dehydrogenase, N-terminal domain/Acy
— OG7
LAMA_000358100 ⚠
Aldehyde dehydrogenase family, putative
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000503100 ⚠
Glycine cleavage system P-protein, putative
— OG7
LAMA_000444800 ⚠
SET domain containing protein, putative
— OG7
LAMA_000603100 ⚠
Queuine tRNA-ribosyltransferase, putative
— OG7
LAMA_000452800 ⚠
GAF domain/TIP41-like family, putative
— OG7
LAMA_000547000 ⚠
50S ribosome-binding GTPase/Ferrous iron tran
— OG7
LAMA_000686600 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LAMA_000552500 ⚠
50S ribosome-binding GTPase/Protein of unknow
— OG7
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
LAMA_000635700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAMA_000206400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000534900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000299100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000239600 ⚠
Proliferating cell nuclear antigen, N-termina
— OG7
LAMA_000128200 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000109100 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAMA_000189200 ⚠
Phosphoglucose isomerase, putative
— Both
LAMA_000084200 ⚠
SET domain/MYND finger containing protein, pu
— OG7
LAMA_000444600 ⚠
SET domain containing protein, putative
— OG7
LAMA_000136500 ⚠
SET domain containing protein, putative
— OG7
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000700000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
LAMA_000119300 ⚠
Amidohydrolase family, putative
— Both
LAMA_000797400 ⚠
FGGY family of carbohydrate kinases, N-termin
— Both
LAMA_000614400 ⚠
Aldehyde dehydrogenase family, putative
— Both
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000211300 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000288700 ⚠
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000434700 ⚠
AhpC/TSA family/Redoxin/C-terminal domain of
— Both
LAMA_000061200 ⚠
Fructose-1-6-bisphosphatase, N-terminal domai
— Both
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— Both
LAMA_000240700 ⚠
hypothetical protein, conserved
— Both
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000620700 ⚠
S-adenosylmethionine synthetase, N-terminal d
— Both
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000434800
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000688100 ⚠
Glucosamine-6-phosphate isomerases/6-phosphog
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.