LAMA_000136500

SET domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_158127 OG7: OG7_0001287 40 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 40 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG7
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000178900 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000261900 ⚠
Probable N6-adenine methyltransferase, putati
— OG7
LAMA_000171700 ⚠
NIF3 (NGG1p interacting factor 3), putative
— OG7
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000503100 ⚠
Glycine cleavage system P-protein, putative
— OG7
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000111000 ⚠
Putative diphthamide synthesis protein, putat
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000186600 ⚠
Pyridoxal-dependent decarboxylase, pyridoxal
— OG7
LAMA_000430100 ⚠
WD domain, G-beta repeat, putative
— OG7
LAMA_000186800 ⚠
SAC3/GANP family, putative
— OG7
LAMA_000100500 ⚠
Inosine-uridine preferring nucleoside hydrola
— OG7
LAMA_000289600 ⚠
Glutamate-cysteine ligase, putative
— OG7
LAMA_000077300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000548400 ⚠
LSM domain containing protein, putative
— Both
LAMA_000468600 ⚠
hypothetical protein, conserved
— Both
LAMA_000295800 ⚠
hypothetical protein, conserved
— Both
LAMA_000633600 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000362600 ⚠
tRNA synthetases class I (I, L, M and V)/Anti
— Both
LAMA_000337600 ⚠
EF-hand domain pair, putative
— OG7
LAMA_000369900 ⚠
Homocysteine S-methyltransferase, putative
— OG7
LAMA_000774700 ⚠
Proteasome activator pa28 beta subunit, putat
— OG7
LAMA_000354900 ⚠
Protein of unknown function (DUF1749), putati
— OG7
LAMA_000600000 ⚠
Peptidase family M20/M25/M40/Peptidase dimeri
— Both
LAMA_000752900 ⚠
EF-hand domain pair/EF hand, putative
— OG7
LAMA_000598600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000293000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000016200 ⚠
Dipeptidyl peptidase IV (DPP IV) N-terminal r
— OG7
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000720800 ⚠
Putative diphthamide synthesis protein, putat
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.