LAMA_000100500

Inosine-uridine preferring nucleoside hydrolase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_124384 OG7: OG7_0003875 32 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 32 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— Both
LAMA_000084200 ⚠
SET domain/MYND finger containing protein, pu
— OG7
LAMA_000444600 ⚠
SET domain containing protein, putative
— OG7
LAMA_000136500 ⚠
SET domain containing protein, putative
— OG7
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000700000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000724600 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000724900 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000502300 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730500 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000296700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000374200
Metalloenzyme superfamily/BPG-independent PGA
— Both
LAMA_000547400 ⚠
CHAP domain/Glutathionylspermidine synthase p
— Both
LAMA_000342600 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000430100
WD domain, G-beta repeat, putative
— Both
LAMA_000549400
Ribonucleotide reductase, small chain, putati
— Both
LAMA_000289600
Glutamate-cysteine ligase, putative
— Both
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000730600 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000444800 ⚠
SET domain containing protein, putative
— Both
LAMA_000583700
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000213400
Threonine synthase N terminus, putative
— Both
LAMA_000042700 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— Both
LAMA_000510000
Aspartate-ammonia ligase, putative
— Both
LAMA_000055800
Spermidine synthase tetramerisation domain/Sp
— Both
LAMA_000598700
Phosphomethylpyrimidine kinase/pfkB family ca
— Both
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.