LAMA_000502300

CHAP domain/Glutathionylspermidine synthase preATP-grasp, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_200119 OG7: OG7_0010828 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000510000 ⚠
Aspartate-ammonia ligase, putative
— OG7
LAMA_000030200 ⚠
AMP-binding enzyme, putative
— OG7
LAMA_000356700 ⚠
Initiation factor 2 subunit family, putative
— OG7
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000021200 ⚠
Hsp70 protein, putative
— OG7
LAMA_000461500 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000078600 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000277500 ⚠
Ubiquitin-like domain/CAP-Gly domain containi
— OG7
LAMA_000461400 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000147800 ⚠
Prolyl oligopeptidase, N-terminal beta-propel
— OG7
LAMA_000148500 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG7
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG7
LAMA_000598700 ⚠
Phosphomethylpyrimidine kinase/pfkB family ca
— OG7
LAMA_000080400 ⚠
dUTPase, putative
— OG7
LAMA_000055800 ⚠
Spermidine synthase tetramerisation domain/Sp
— OG7
LAMA_000009700 ⚠
Paraflagellar rod protein, putative
— OG7
LAMA_000032500 ⚠
AMP-binding enzyme, putative
— OG7
LAMA_000549200 ⚠
Amino-transferase class IV, putative
— OG7
LAMA_000549700 ⚠
Amino-transferase class IV, putative
— OG7
LAMA_000042700 ⚠
AMP-binding enzyme, putative
— OG7
LAMA_000213400 ⚠
Threonine synthase N terminus, putative
— OG7
LAMA_000100500 ⚠
Inosine-uridine preferring nucleoside hydrola
— OG7
LAMA_000547200 ⚠
Paraflagellar rod protein/Variant SH3 domain/
— OG7
LAMA_000374200 ⚠
Metalloenzyme superfamily/BPG-independent PGA
— OG7
LAMA_000440100 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— OG7
LAMA_000549400 ⚠
Ribonucleotide reductase, small chain, putati
— OG7
LAMA_000730800 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000719300 ⚠
PPPDE putative peptidase domain/PUB domain/Gl
— Both
LAMA_000338600 ⚠
14-3-3 protein, putative
— Both
LAMA_000173900 ⚠
14-3-3 protein, putative
— Both
LAMA_000410500 ⚠
Adenylate kinase/AAA domain containing protei
— Both
LAMA_000157000 ⚠
Thymidylate kinase, putative
— Both
LAMA_000499300 ⚠
KIF-1 binding protein C terminal, putative
— Both
LAMA_000412300 ⚠
hypothetical protein, conserved
— Both
LAMA_000054600 ⚠
hypothetical protein, conserved
— Both
LAMA_000241400 ⚠
ASF1 like histone chaperone, putative
— Both
LAMA_000296700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730500 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730600 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000730700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000081100
Putative Phosphatase/Protein of unknown funct
— OG6
LAMA_000583700 ⚠
lactate/malate dehydrogenase, NAD binding dom
— OG7
LAMA_000031800 ⚠
Hsp70 protein, putative
— OG7
LAMA_000362000 ⚠
Aminopeptidase P, N-terminal domain/Metallope
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.