LAMA_000080400

dUTPase, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_134368 OG7: OG7_0034055 18 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 18 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000320800
hypothetical protein, conserved
— Both
LAMA_000724600 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000724900 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000502300 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000431100
Polyprenyl synthetase, putative
— Both
LAMA_000547400 ⚠
CHAP domain/Glutathionylspermidine synthase p
— Both
LAMA_000670800
NAD synthase, putative
— Both
LAMA_000645300
Haloacid dehalogenase-like hydrolase/HAD-hyro
— Both
LAMA_000717000
hypothetical protein, conserved
— Both
LAMA_000313200
Protein kinase domain/Protein tyrosine kinase
— OG6
LAMA_000499300
KIF-1 binding protein C terminal, putative
— Both
LAMA_000583700
lactate/malate dehydrogenase, NAD binding dom
— Both
LAMA_000055800
Spermidine synthase tetramerisation domain/Sp
— Both
LAMA_000410500 ⚠
Adenylate kinase/AAA domain containing protei
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.