LAMA_000549400

Ribonucleotide reductase, small chain, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100537 OG7: OG7_0003661 80 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 80 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000328100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000298700 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000661500 ⚠
Leucine rich repeat, putative
— OG7
LAMA_000304200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000186600
Pyridoxal-dependent decarboxylase, pyridoxal
— Both
LAMA_000384900
hypothetical protein, conserved
— Both
LAMA_000374200
Metalloenzyme superfamily/BPG-independent PGA
— Both
LAMA_000115400 ⚠
Hsp70 protein/Tetratricopeptide repeat, putat
— Both
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000362300
Adenylate cyclase associated (CAP) N terminal
— Both
LAMA_000719300
PPPDE putative peptidase domain/PUB domain/Gl
— Both
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000812000
SET domain containing protein, putative
— Both
LAMA_000495000
hypothetical protein, conserved
— Both
LAMA_000513800 ⚠
Leucine Rich repeat, putative
— Both
LAMA_000786400 ⚠
hypothetical protein, conserved
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000715300
Histone-binding protein RBBP4 or subunit C of
— Both
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000724600 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000724900 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000239500 ⚠
tRNA synthetases class I (E and Q), catalytic
— OG7
LAMA_000502300 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LAMA_000371900
Sec23/Sec24 zinc finger/Sec23/Sec24 trunk dom
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000157800 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000165200 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000575700 ⚠
DEAD/DEAH box helicase/Type III restriction e
— Both
LAMA_000091100 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000356200 ⚠
Leucine rich repeat/Leucine-rich repeat, puta
— OG7
LAMA_000797600 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000744000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000129500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000437500 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000431800 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000307900 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LAMA_000235700
ThiF family, putative
— Both
LAMA_000100500
Inosine-uridine preferring nucleoside hydrola
— Both
LAMA_000213400
Threonine synthase N terminus, putative
— Both
LAMA_000618000 ⚠
tRNA synthetases class I (E and Q), catalytic
— Both
LAMA_000510000
Aspartate-ammonia ligase, putative
— Both
LAMA_000239600
Proliferating cell nuclear antigen, N-termina
— Both
LAMA_000055800
Spermidine synthase tetramerisation domain/Sp
— Both
LAMA_000547400 ⚠
CHAP domain/Glutathionylspermidine synthase p
— Both
LAMA_000598700
Phosphomethylpyrimidine kinase/pfkB family ca
— Both
LAMA_000042100
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.