LAMA_000547200

Paraflagellar rod protein/Variant SH3 domain/SH3 domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146420 OG7: OG7_0018585 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000278400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000101700 ⚠
FYVE zinc finger/3'5'-cyclic nucleotide phosp
— OG7
LAMA_000502300 ⚠
CHAP domain/Glutathionylspermidine synthase p
— OG7
LAMA_000542600 ⚠
Arginyl tRNA synthetase N terminal domain/tRN
— OG7
LAMA_000362000 ⚠
Aminopeptidase P, N-terminal domain/Metallope
— OG7
LAMA_000141900 ⚠
AAA domain (dynein-related subfamily)/AAA dom
— OG7
LAMA_000813600 ⚠
Hsp70 protein, putative
— OG7
LAMA_000510500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000284200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000240000 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000735200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000724900 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000724600 ⚠
CHAP domain containing protein, putative
— OG7
LAMA_000299400 ⚠
Phe-tRNA synthetase beta subunit B1 domain/B3
— OG7
LAMA_000240100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000240300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000164400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAMA_000240200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000286500 ⚠
Hsp70 protein, putative
— OG7
LAMA_000406700 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LAMA_000022000 ⚠
hypothetical protein, conserved
— OG7
LAMA_000104000 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000104800 ⚠
Aminopeptidase I zinc metalloprotease (M18)/M
— OG7
LAMA_000268200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000625300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000196000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000122000 ⚠
Radial spokehead-like protein, putative
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000790100 ⚠
Aminopeptidase P, N-terminal domain/Metallope
— Both
LAMA_000547400 ⚠
CHAP domain/Glutathionylspermidine synthase p
— Both
LAMA_000510000 ⚠
Aspartate-ammonia ligase, putative
— Both
LAMA_000342600 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— Both
LAMA_000567600 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000514000 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— Both
LAMA_000021200 ⚠
Hsp70 protein, putative
— Both
LAMA_000583300 ⚠
Hsp70 protein/MreB/Mbl protein, putative
— OG6
LAMA_000461500 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000260200 ⚠
Pyridoxal-phosphate dependent enzyme, putativ
— OG6
LAMA_000461400 ⚠
Malic enzyme, N-terminal domain/Malic enzyme,
— Both
LAMA_000148500 ⚠
Uncharacterised protein family (UPF0160), put
— Both
LAMA_000440100 ⚠
AMP-binding enzyme/AMP-binding enzyme C-termi
— Both
LAMA_000119300 ⚠
Amidohydrolase family, putative
— Both
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000050100 ⚠
MORN repeat, putative
— OG7
LAMA_000073300 ⚠
MORN repeat, putative
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.