LAMA_000625300

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_103837 OG7: OG7_0009742 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000104800
Aminopeptidase I zinc metalloprotease (M18)/M
— Both
LAMA_000224000 ⚠
tRNA synthetases class I (W and Y), putative
— OG7
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000547200 ⚠
Paraflagellar rod protein/Variant SH3 domain/
— OG7
LAMA_000762800 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000035200 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LAMA_000668800 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000808100 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
LAMA_000181600 ⚠
Elongation factor Tu GTP binding domain/Elong
— Both
LAMA_000422000 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000022000
hypothetical protein, conserved
— Both
LAMA_000138100
Tetratricopeptide repeat/STI1 domain/TPR repe
— OG6
LAMA_000252800 ⚠
Putative tRNA binding domain containing prote
— Both
LAMA_000278400
hypothetical protein, conserved
— Both
LAMA_000616100
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000009700 ⚠
Paraflagellar rod protein, putative
— Both
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— Both
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— Both
LAMA_000542600
Arginyl tRNA synthetase N terminal domain/tRN
— Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.