LAMA_000774700

Proteasome activator pa28 beta subunit, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_132802 OG7: OG7_0037801 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000111000 ⚠
Putative diphthamide synthesis protein, putat
— OG7
LAMA_000362300
Adenylate cyclase associated (CAP) N terminal
— Both
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000444800 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000700000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000136500 ⚠
SET domain containing protein, putative
— OG7
LAMA_000444600 ⚠
SET domain containing protein, putative
— OG7
LAMA_000084200 ⚠
SET domain/MYND finger containing protein, pu
— OG7
LAMA_000797200 ⚠
ThiF family/Ubiquitin-activating enzyme E1 fo
— Both
LAMA_000041000 ⚠
Met-10+ like-protein/Methyltransferase small
— OG7
LAMA_000311400 ⚠
Ubiquitin family/UBA/TS-N domain containing p
— OG7
LAMA_000535800 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000488700 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
LAMA_000357300 ⚠
Tubulin/FtsZ family, GTPase domain containing
— OG7
LAMA_000407400 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000488100 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000014200 ⚠
Tubulin/FtsZ family, GTPase domain/Tubulin C-
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000587400 ⚠
NAD binding domain of 6-phosphogluconate dehy
— Both
LAMA_000232500
hypothetical protein, conserved
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000059600
hypothetical protein, conserved
— Both
LAMA_000040200 ⚠
ATPase family associated with various cellula
— Both
LAMA_000115100 ⚠
Clp amino terminal domain, pathogenicity isla
— Both
LAMA_000201400
hypothetical protein, conserved
— Both
LAMA_000097100
hypothetical protein, conserved
— Both
LAMA_000069500
Vta1 like/Vta1 C-terminal domain containing p
— Both
LAMA_000616000 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000016700 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG6
LAMA_000065700 ⚠
MORN repeat/Protein kinase domain/Protein tyr
— OG6
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000219000
Eukaryotic glutathione synthase, ATP binding
— Both
LAMA_000199900 ⚠
Ubiquitin family, putative
— Both
LAMA_000007300
Ankyrin repeats (many copies)/Ankyrin repeat/
— OG6
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000720800 ⚠
Putative diphthamide synthesis protein, putat
— Both
LAMA_000113600
hypothetical protein, conserved
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000446600
hypothetical protein, conserved
— Both
LAMA_000244600 ⚠
Met-10+ like-protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.