LAMA_000446600

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_199899 OG7: OG7_0043181 22 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 22 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000482300
Translation initiation factor SUI1, putative
— Both
LAMA_000042000 ⚠
ABC transporter, putative
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000013500 ⚠
M17 aminopeptidase N-terminal domain 2, putat
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000126300
RIO1 family, putative
— OG7
LAMA_000590900
Bystin, putative
— OG7
LAMA_000676500
CSN8/PSMD8/EIF3K family, putative
— OG7
LAMA_000138700
hypothetical protein, conserved
— OG7
LAMA_000007300
Ankyrin repeats (many copies)/Ankyrin repeat/
— OG6
LAMA_000232500
hypothetical protein, conserved
— Both
LAMA_000362300
Adenylate cyclase associated (CAP) N terminal
— Both
LAMA_000774700
Proteasome activator pa28 beta subunit, putat
— Both
LAMA_000764200 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000721900 ⚠
M17 aminopeptidase N-terminal domain 2/Cytoso
— Both
LAMA_000775300
hypothetical protein, conserved
— Both
LAMA_000698500 ⚠
ABC transporter, putative
— Both
LAMA_000115100 ⚠
Clp amino terminal domain, pathogenicity isla
— Both
LAMA_000040200 ⚠
ATPase family associated with various cellula
— Both
LAMA_000219000
Eukaryotic glutathione synthase, ATP binding
— Both
LAMA_000201400
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.