LAMA_000354900

Protein of unknown function (DUF1749), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_108229 OG7: OG7_0012620 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000789800 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000610900 ⚠
hypothetical protein, conserved
— OG7
LAMA_000530200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000444800 ⚠
SET domain containing protein, putative
— OG7
LAMA_000471700 ⚠
SET domain containing protein, putative
— OG7
LAMA_000790000 ⚠
CAF1 family ribonuclease, putative
— OG7
LAMA_000739200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000700000 ⚠
SET domain containing protein, putative
— OG7
LAMA_000193200 ⚠
SET domain containing protein, putative
— OG7
LAMA_000136500 ⚠
SET domain containing protein, putative
— OG7
LAMA_000444600 ⚠
SET domain containing protein, putative
— OG7
LAMA_000084200 ⚠
SET domain/MYND finger containing protein, pu
— OG7
LAMA_000111000 ⚠
Putative diphthamide synthesis protein, putat
— OG7
LAMA_000172900 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000788200 ⚠
Adenosine/AMP deaminase, putative
— OG7
LAMA_000769800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000498700 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000104400 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000504100 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000801900 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000792600 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000655200 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000375500 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAMA_000572100 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000679200 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000624900 ⚠
N-terminal domain of 16S rRNA methyltransfera
— OG7
LAMA_000108400 ⚠
16S rRNA methyltransferase RsmB/F, putative
— OG7
LAMA_000705700 ⚠
PSP1 C-terminal conserved region containing p
— Both
LAMA_000325800
hypothetical protein, conserved
— Both
LAMA_000536900
Right handed beta helix region/Periplasmic co
— Both
LAMA_000210000
KH domain containing protein, putative
— Both
LAMA_000214100
mRNA capping enzyme, beta chain, putative
— Both
LAMA_000499300
KIF-1 binding protein C terminal, putative
— Both
LAMA_000672000
hypothetical protein, conserved
— Both
LAMA_000197100
hypothetical protein, conserved
— Both
LAMA_000493100 ⚠
PUA domain/16S rRNA methyltransferase RsmB/F,
— Both
LAMA_000164000
hypothetical protein, conserved
— Both
LAMA_000402900 ⚠
hypothetical protein, conserved
— Both
LAMA_000475600
Hydroxymethylglutaryl-coenzyme A synthase N t
— Both
LAMA_000623000
Cobalamin-independent synthase, N-terminal do
— Both
LAMA_000705600 ⚠
hypothetical protein, conserved
— Both
LAMA_000106300
Leucine-rich repeat/Leucine rich repeat, puta
— Both
LAMA_000564200
ATP cone domain/Ribonucleotide reductase, all
— Both
LAMA_000618900
hypothetical protein, conserved
— Both
LAMA_000717000
hypothetical protein, conserved
— Both
LAMA_000471500 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000440900 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000720800 ⚠
Putative diphthamide synthesis protein, putat
— Both
LAMA_000370600 ⚠
CAF1 family ribonuclease, putative
— Both
LAMA_000441000 ⚠
CAF1 family ribonuclease, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.