LAMA_000358100

Aldehyde dehydrogenase family, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_137430 OG7: OG7_0000714 11 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 11 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000615100 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000813900 ⚠
Glyceraldehyde 3-phosphate dehydrogenase, NAD
— OG7
LAMA_000620700 ⚠
S-adenosylmethionine synthetase, N-terminal d
— OG7
LAMA_000797400 ⚠
FGGY family of carbohydrate kinases, N-termin
— OG7
LAMA_000814600 ⚠
Histidine phosphatase superfamily (branch 1),
— OG7
LAMA_000107000 ⚠
ERG2 and Sigma1 receptor like protein, putati
— OG7
LAMA_000190100 ⚠
Aminotransferase class I and II, putative
— OG7
LAMA_000691300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000456800 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— OG7
LAMA_000109000 ⚠
Fumarate hydratase (Fumerase)/Fumarase C-term
— OG7
LAMA_000204500 ⚠
Adenylosuccinate synthetase, putative
— OG7
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.