LAMA_000791100

HECT-domain (ubiquitin-transferase), putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_146796 OG7: OG7_0002947 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000236100 ⚠
Bacterial NAD-glutamate dehydrogenase/Glutama
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000374800 ⚠
DNA polymerase III, delta subunit/ATPase fami
— OG7
LAMA_000612400 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000799300 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000534400 ⚠
Rad17 P-loop domain/DNA polymerase III, delta
— OG7
LAMA_000388300 ⚠
hypothetical protein, conserved
— OG7
LAMA_000263200 ⚠
ATPase family associated with various cellula
— OG7
LAMA_000593200 ⚠
GrpE, putative
— OG7
LAMA_000593300 ⚠
GrpE, putative
— OG7
LAMA_000720700 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000515300 ⚠
Ferrous iron transport protein B/50S ribosome
— OG7
LAMA_000818600 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAMA_000066600 ⚠
NGP1NT (NUC091) domain/Ferrous iron transport
— OG7
LAMA_000347400 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— OG7
LAMA_000696800 ⚠
Cytosolic carboxypeptidase N-terminal domain/
— OG7
LAMA_000131800 ⚠
Isochorismatase family, putative
— OG7
LAMA_000437600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000184300 ⚠
Isochorismatase family, putative
— OG7
LAMA_000811100 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000131000 ⚠
ThiF family/Ubiquitin/SUMO-activating enzyme
— OG7
LAMA_000509300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000495300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000032800 ⚠
ThiF family, putative
— OG7
LAMA_000502800 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000509400 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000665000 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000598300 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000174600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000027400 ⚠
LSM domain containing protein, putative
— OG7
LAMA_000260100 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000347700 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000332000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000649300 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAMA_000784100 ⚠
Ubiquitin carboxyl-terminal hydrolase/ICP0-bi
— OG7
LAMA_000237800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000299500 ⚠
hypothetical protein, conserved
— OG7
LAMA_000245400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAMA_000514400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000506600 ⚠
hypothetical protein, conserved
— OG7
LAMA_000732400 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAMA_000432300 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000070000 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAMA_000103600 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000150500 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
LAMA_000288600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000167900 ⚠
Zinc finger, C3HC4 type (RING finger)/Prokary
— OG7
LAMA_000153000 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAMA_000386700 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.