LAMA_000801700

FYVE zinc finger containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_127004 OG7: OG7_0001169 236 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 236 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000253000 ⚠
WW domain containing protein, putative
— Both
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000178900 ⚠
Leucine Rich repeat, putative
— OG7
LAMA_000619700 ⚠
Dynein heavy chain region D6 P-loop domain co
— OG7
LAMA_000588300 ⚠
Ubiquitin carboxyl-terminal hydrolase/Exonucl
— OG7
LAMA_000751700 ⚠
RNA-binding signal recognition particle 68, p
— OG7
LAMA_000329200 ⚠
Gamma tubulin complex component N-terminal, p
— OG7
LAMA_000358900 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000626600 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— OG7
LAMA_000418000 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
LAMA_000516300 ⚠
Prenyltransferase and squalene oxidase repeat
— OG7
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000122600 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAMA_000661400 ⚠
Pan3 Pseudokinase domain containing protein,
— OG7
LAMA_000285400 ⚠
Aminoacyl-tRNA editing domain/tRNA synthetase
— OG7
LAMA_000746000 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LAMA_000536900 ⚠
Right handed beta helix region/Periplasmic co
— OG7
LAMA_000794200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAMA_000626200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000723700 ⚠
Elongation factor Tu GTP binding domain/50S r
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000609800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000591800 ⚠
hypothetical protein, conserved
— OG7
LAMA_000358700 ⚠
Glycosyl hydrolase family 65, N-terminal doma
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000622600 ⚠
CPSF A subunit region containing protein, put
— OG7
LAMA_000071000 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
LAMA_000071100 ⚠
CPSF A subunit region containing protein, put
— OG7
LAMA_000179200 ⚠
PUB domain containing protein, putative
— OG7
LAMA_000410500 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000281500 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000668200 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000267800 ⚠
N-terminal helicase PWI domain/DEAD/DEAH box
— OG7
LAMA_000197500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000440400 ⚠
hypothetical protein, conserved
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000295900 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000174100 ⚠
hypothetical protein, conserved
— OG7
LAMA_000012800 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.