LAMA_000197500

DEAD/DEAH box helicase/Type III restriction enzyme, res subunit/Sec63 Brl domain/Helicase conserved C-terminal domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100305 OG7: OG7_0001850 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000806000 ⚠
PRO8NT (NUC069), PrP8 N-terminal domain/PROCN
— Both
LAMA_000477400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000576100 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000253800 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000016100 ⚠
Cullin protein neddylation domain containing
— OG7
LAMA_000336900 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— Both
LAMA_000019300 ⚠
Cullin family, putative
— Both
LAMA_000370000 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000435500 ⚠
Beige/BEACH domain containing protein, putati
— Both
LAMA_000109600 ⚠
hypothetical protein, conserved
— Both
LAMA_000335600 ⚠
Phosphatidylinositol 3- and 4-kinase, putativ
— Both
LAMA_000232600 ⚠
hypothetical protein, conserved
— Both
LAMA_000281400 ⚠
hypothetical protein, conserved
— Both
LAMA_000681500 ⚠
SpoU rRNA Methylase family, putative
— Both
LAMA_000742200 ⚠
hypothetical protein, conserved
— Both
LAMA_000215700 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— Both
LAMA_000236700 ⚠
hypothetical protein, conserved
— Both
LAMA_000036700 ⚠
26S proteasome regulatory subunit RPN6 N-term
— Both
LAMA_000694100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LAMA_000020200 ⚠
PCI domain/Proteasome regulatory subunit C-te
— Both
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000676700 ⚠
Elongation factor Tu GTP binding domain/50S r
— Both
LAMA_000350900 ⚠
Proteasomal ATPase OB C-terminal domain/Holli
— OG6
LAMA_000697700 ⚠
WD domain, G-beta repeat, putative
— Both
LAMA_000675800 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000768000 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAMA_000767100 ⚠
Domain of unknown function (DUF3385)/FAT doma
— OG7
LAMA_000732900 ⚠
RNA polymerase Rpb1, domain 1/RNA polymerase
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000470800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000079700 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAMA_000453900 ⚠
Beige/BEACH domain containing protein, putati
— OG7
LAMA_000388600 ⚠
FAT domain/Phosphatidylinositol 3- and 4-kina
— OG7
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000180100 ⚠
Adaptin N terminal region/non-SMC mitotic con
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000624500 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000307500 ⚠
Elongation factor Tu GTP binding domain/Elong
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.